What happens if you take 9 tylenol

If necessary, an antidote might be given to reverse the effects of the acetaminophen. Before you give your child acetaminophen, consider whether he or she needs it. For example, the main goal of treating a child who has a fever is to improve his or her comfort — not to normalize his or her body temperature.

In addition:. Careful use of acetaminophen and prompt treatment in case of an overdose can help prevent a tragedy. Mayo Clinic does not endorse companies or products.

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Take the correct dose While you're looking at the label, check to make sure you're taking the correct dose, especially if it's extended-release acetaminophen. Don't take more than one type of acetaminophen at a time Since many medicines contain it, make sure that the total dose you take doesn't exceed 4, milligrams or 4 grams in one day. Plus, the acetaminophen in one medicine can address all of the aches and pains you may be taking multiple medicines for.

Don't take it for too many days in a row "Don't take acetaminophen for more than 10 days to treat pain and don't take it for more than three days for a fever," Grassi said. The basis for diagnosis and treatment of acetaminophen overdose is the serum acetaminophen concentration. This is helpful even in the absence of clinical symptoms, because these symptoms are delayed. The Rumack-Matthew nomogram is predictive of possible hepatotoxicity after single, acute ingestions of acetaminophen.

In addition to the laboratory findings discussed in TABLE 1 , the following analyses are recommended to facilitate diagnosis:.

Pharmacokinetics: Ingested acetaminophen is rapidly absorbed from the stomach and small intestine. The serum concentration peaks 1 to 2 hours post ingestion. Peak plasma levels occur within 4 hours after ingestion of an overdose of an immediate-release preparation. In patients with underlying hepatic dysfunction, the half-life may last as long as 17 hours post ingestion. The evaluation and treatment approach for an IV acetaminophen overdose are similar to those for an oral overdose. Activated charcoal is administered if the patient is alert and presents within 1 hour post ingestion.

Oral activated charcoal quickly adsorbs acetaminophen. The Rumack-Matthew nomogram or, acetaminophen-toxicity nomogram plots the serum acetaminophen concentration against the time since ingestion to predict possible liver toxicity, as well as allow the clinician to decide whether to proceed with NAC treatment. It is a logarithmic graph starting not directly from ingestion, but from 4 hours post ingestion, after absorption is considered likely to be complete.

This nomogram allows for the timely management of acetaminophen overdose. NAC is approved for both oral and IV administration. Use within 1 hour of preparation for a total treatment of 72 hours. Liver Transplantation: In severe hepatotoxicity leading to progression to liver failure, liver transplantation is the last resort.

Acetaminophen can be fatal in overdose, but many people underestimate the potential dangers of this medication. The initial manifestations of acetaminophen poisoning are often mild and nonspecific, and they do not reliably predict subsequent hepatotoxicity. Acetaminophen is rapidly and completely absorbed from the GI tract.

Serum concentrations peak between 30 minutes and 2 hours after an oral therapeutic dose. Acetaminophen-induced hepatitis is acute in onset and progresses rapidly. Therefore, measurement of the serum acetaminophen concentration is critical whenever overdose is suspected. The risk of toxicity is best predicted by relating the time of ingestion to the serum acetaminophen concentration. Following a single acute overdose of an immediate-release preparation, a serum acetaminophen concentration should be drawn 4 hours after reported ingestion.

The level should be evaluated, according to the Rumack-Matthew nomogram, to determine the need for treatment with NAC. Clin Toxicol Phila. Want monthly health tips emailed to you? Sign up here! First Name. Last Name. Tags health tips pain prevention liver. Post a Comment. Name: Name: must have at least 0 and no more than characters.